Freezing nerves during lung transplant may cut pain and morphine use

NCT ID NCT06959056

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests a technique called cryo-analgesia, where doctors freeze chest nerves during double lung transplant surgery. The goal is to see if this reduces pain, morphine use, and time in the hospital for people with end-stage COPD. Forty participants will either get the nerve freezing or standard pain treatment, and be followed for one year. It is an early, small study to see if the approach is worth testing in larger trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cryo nerve block (freezing of chest nerves during surgery)

What this could lead to

If it works, this could offer a way to reduce severe chest pain and morphine use after lung transplantation, potentially speeding up recovery.

What could go wrong

This is a very small pilot study with only 40 people, so results may not apply to everyone. The nerve freezing could cause complications or not improve pain enough to change standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospitals Leuven

    RECRUITING

    Leuven, Vlaams-Brabant, 3000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••