Freezing nerves during lung transplant may cut pain and morphine use
NCT ID NCT06959056
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests a technique called cryo-analgesia, where doctors freeze chest nerves during double lung transplant surgery. The goal is to see if this reduces pain, morphine use, and time in the hospital for people with end-stage COPD. Forty participants will either get the nerve freezing or standard pain treatment, and be followed for one year. It is an early, small study to see if the approach is worth testing in larger trials.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cryo nerve block (freezing of chest nerves during surgery)
- What this could lead to
- If it works, this could offer a way to reduce severe chest pain and morphine use after lung transplantation, potentially speeding up recovery.
- What could go wrong
- This is a very small pilot study with only 40 people, so results may not apply to everyone. The nerve freezing could cause complications or not improve pain enough to change standard care.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Hospitals Leuven
RECRUITINGLeuven, Vlaams-Brabant, 3000, Belgium
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