Can a natural supplement soothe diabetic nerve pain?
NCT ID NCT07377409
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a dietary supplement called Cronilief (palmitoylethanolamide) can reduce nerve pain in people with diabetes when added to their usual treatment. Seventy adults with moderate nerve pain will take either the supplement or a placebo for 8 weeks. The goal is to see if it improves pain and sleep quality.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cronilief (palmitoylethanolamide phospholipids)
What this could lead to
If it works, this could offer a natural supplement option to help manage nerve pain in people with diabetes.
What could go wrong
This is a small, early-stage trial with only 70 people. The supplement may not work better than placebo, and results may not apply to everyone with diabetic nerve pain.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.