Can a natural supplement soothe diabetic nerve pain?

NCT ID NCT07377409

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a dietary supplement called Cronilief (palmitoylethanolamide) can reduce nerve pain in people with diabetes when added to their usual treatment. Seventy adults with moderate nerve pain will take either the supplement or a placebo for 8 weeks. The goal is to see if it improves pain and sleep quality.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Cronilief (palmitoylethanolamide phospholipids)
What this could lead to
If it works, this could offer a natural supplement option to help manage nerve pain in people with diabetes.
What could go wrong
This is a small, early-stage trial with only 70 people. The supplement may not work better than placebo, and results may not apply to everyone with diabetic nerve pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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