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Creatine may boost heat adaptation in athletes, new study suggests

NCT ID NCT07593014

Knowledge-focused Sponsor: University of Windsor Source: ClinicalTrials.gov ↗

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Cancelled before anyone took part.

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First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether taking creatine supplements helps the body adapt to exercising in hot conditions. Healthy men aged 18-27 will take either creatine or a placebo daily while doing supervised workouts in a heated room. Researchers will measure changes in hydration, blood volume, and exercise performance to see if creatine offers any extra benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 25 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 27 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy biological males between 18 and 27 years of age * Recreationally active males and varsity athletes * Able to safely participate in moderate-intensity exercise and heat exposure * Willing to maintain habitual diet and physical activity throughout the study * Willing to refrain from additional dietary supplementation during study participation * Able to attend all required laboratory visits and heat exposure sessions * Able to provide informed consent Exclusion Criteria: * History of cardiovascular, metabolic, respiratory, renal, neurological, or heat-related illness * Contraindications to exercise testing or heat exposure identified during health screening * Current musculoskeletal injury limiting exercise participation * Current use of creatine supplementation or inability to complete the required washout period * Current use of medications or supplements known to affect hydration, thermoregulation, cardiovascular function, or exercise performance * Known allergy or intolerance to creatine monohydrate, maltodextrin, or orange juice * Inability to comply with study procedures or supplementation protocol * Resting tympanic temperature ≥38.0°C prior to a heat exposure session * Participation in another research study that may interfere with this protocol

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Body fluid compartments Creatine supplementation Exercise performance Heat exposure Hydration Placebo - control Plasma volume

How to take part

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  1. The official record

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