Creatine plus resistance training may help prostate cancer patients preserve muscle
NCT ID NCT06112990
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether taking creatine supplements along with a home-based resistance training program can help men with metastatic prostate cancer maintain muscle mass and reduce fatigue. Two hundred participants will be randomly assigned to receive either creatine or a placebo, plus supervised exercise twice a week for 52 weeks. The goal is to improve physical function and quality of life during hormone therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- creatine monohydrate (a dietary supplement)
- What this could lead to
- If it works, this could offer a safe, non-drug way to help men with advanced prostate cancer maintain muscle, reduce fatigue, and improve quality of life during hormone therapy.
- What could go wrong
- This is a phase 3 trial but still experimental. The supplement may not provide significant benefit over exercise alone, and results may not apply to all patients. No serious risks are expected, but individual responses vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Huntsman Cancer Institute
RECRUITINGSalt Lake City, Utah, 84112, United States
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- A PET scan and a blood test may predict which men with advanced prostate cancer will benefit from targeted therapy