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Cranberry extract: a berry for the belly and the brain?

NCT ID NCT05062954

Disease control Sponsor: Laval University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time

Summary

This trial tests whether a daily cranberry extract supplement, rich in polyphenols, can improve metabolic and cognitive health in adults with abdominal obesity. Over 8 weeks, participants take either the extract or a placebo, and researchers measure changes in blood sugar, cholesterol, and brain function. The goal is to see if this natural compound could offer a simple way to support heart and brain health in this population.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Polyphenol-rich cranberry extract standardized in proanthocyanidins (PACs)
What this could lead to
If effective, this could point toward a natural supplement to improve metabolic and cognitive health in people with abdominal obesity.
What could go wrong
This is a small, early-stage trial, and results may not apply broadly. The supplement may not produce significant benefits, and individual responses can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

49 people

The number who actually took part.

Started

Oct 2021

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * Men and women aged between 30-70 years old; * BMI equal or greater than 25 kg/m2; * Waist circumference ≥85 cm for women, ≥90 cm for men; * Stable weight in the past 3 months; * Plasma triglycerides levels ≥1.5 mmol/L for men and women; * Access to a computer and Internet. Exclusion criteria: * Any severe uncontrolled medical, surgical, neurological or psychiatric condition; * Medication for dyslipidemias, CVD, T2D or obesity; * Medication that may affect the CNS; * Gastro-intestinal conditions or disorders likely to impact on absorption; * History of nephrolithiasis or urolithiasis; * Contraindications to MRI (cardiac pacemaker/defibrillator, cochlear implant or other ear implant, implanted insulin pump or other infusion pump systems, neurostimulator or other electronic/magnetic implant or device, any type of prothesis, aneurysm clips, any metallic fragments, vascular access port, catheter, dental retainer, claustrophobia, surgery in the last 3 months); * Anticoagulant/blood thinning medication in the last month; * Pregnant or breastfeeding women; * Substance or alcohol abuse; * Known allergy or intolerance to cranberry; * Currently smoking.

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Conditions

The condition(s) this trial relates to.

Obesity, Abdominal

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abdominal obesity

Contacts and locations

Locations

  • Quebec Heart and Lung Institute - Laval University

    Québec, Quebec, G1V 4G5, Canada

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