Oxford COVID-19 vaccine shows promise in early trial

NCT ID NCT04324606

Completed ⭐️ VACCINE ⭐️ Sponsor: University of Oxford Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a new COVID-19 vaccine called ChAdOx1 nCoV-19 in over 1,000 healthy adults aged 18-55 in the UK. The goal was to see if the vaccine is safe, triggers an immune response, and can prevent COVID-19. Participants received either the vaccine or a comparison shot, and some got a booster dose.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ChAdOx1 nCoV-19 vaccine
What this could lead to: If successful, this vaccine could help protect people from COVID-19 and reduce the spread of the virus.
What could go wrong: This is an early-phase trial with a limited number of healthy adults, so results may not apply to everyone. The vaccine may cause side effects or prove less effective in larger, more diverse populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Coronavinae infectious disease Orthocoronavirinae infectious disease COVID-19 prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONAVIRUS

Contacts and locations

Locations

CCVTM, University of Oxford, Churchill Hospital

Oxford, OX3 7LE, United Kingdom
Imperial College Healthcare NHS Trust

London, W2 1NY, United Kingdom
John Radcliffe Hospital

Oxford, OX3 9DU, United Kingdom
St Georges University Hospital NHS Foundation Trust

London, SW17 0QT, United Kingdom
University Hospital Southampton NHS Foundation Trust

Southampton, Hampshire, SO16 6YD, United Kingdom
University Hospitals Bristol and Weston NHS Foundation Trust

Bristol, BS1 3NU, United Kingdom

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