Scientists probe immune system in severe COVID-19 to find new clues

NCT ID NCT04392401

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 200 adults with COVID-19 in intensive care to see how their immune systems change over time. Researchers will collect blood samples at several points during the hospital stay and track health outcomes. The goal is to understand why some patients get worse and to find new ways to treat or prevent severe illness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help identify new treatments and biological markers to better manage COVID-19 in intensive care.

What could go wrong

This is an observational study, not testing a treatment. It may not directly lead to new therapies, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CH de St Etienne

    NOT_YET_RECRUITING

    Saint-Etienne, 42055, France

    Contact

  • Centre hospitalier universitaire de Grenoble Alpes

    NOT_YET_RECRUITING

    Grenoble, 38043, France

    Contact

  • Hôpial de la Croix Rousse

    RECRUITING

    Lyon, 69004, France

    Contact

  • Hôpital Edouard Herriot

    RECRUITING

    Lyon, 69003, France

  • Hôpital Edouard Herriot

    RECRUITING

    Lyon, 69003, France

    Contact

    Contact

  • Hôpital Gabriel Montpied

    NOT_YET_RECRUITING

    Clermont-Ferrand, 63000, France

    Contact

  • Hôpital Lyon Sud

    RECRUITING

    Pierre-Bénite, 69310, France

    Contact

  • Hôpital Pierre Wertheimer

    RECRUITING

    Bron, 69500, France

    Contact