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Knee injection study hopes to ease arthritis pain in children

NCT ID NCT07709026

Symptom relief Sponsor: Necmettin Erbakan University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study looks at how corticosteroid injections into the knee joint affect pain, movement, and daily function in children and teens with juvenile idiopathic arthritis (JIA). Researchers measure changes before the injection, two weeks after, and two months after. The goal is to understand the short-term benefits of this common treatment for young patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a corticosteroid injection into the knee joint
What this could lead to
If successful, this could confirm that corticosteroid injections provide meaningful short-term relief and functional improvement for children with JIA knee arthritis.
What could go wrong
This is a small, non-randomized study with only 17 participants, so results may not apply to all children. Benefits may be temporary and not outweigh risks like joint damage or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

17 people

The number who actually took part.

Started

Nov 2022

Finished

Aug 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of pediatric patients diagnosed with Juvenile Idiopathic Arthritis (JIA) who present with active unilateral or bilateral knee joint involvement. Participants include both newly diagnosed individuals and those under regular follow-up at a tertiary medical center's outpatient clinic, all of whom required clinical knee intra-articular corticosteroid injection (IACI) as part of their routine medical management.

Ages

8 to 16 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients diagnosed with juvenile idiopathic arthritis (JIA) according to standard criteria (arthritis with onset before the age of 16 years and duration longer than 6 weeks with no other identifiable cause). * Having unilateral or bilateral active knee joint arthritis. * Undergoing knee intra-articular corticosteroid injection (IACI) for the active knee joint involvement. * Provision of written informed consent by both patients and their caregivers. Exclusion Criteria: * Presence of other chronic rheumatological diseases. * Initiation or discontinuation of systemic steroids, conventional disease-modifying anti-rheumatic drugs (DMARDs) (e.g., methotrexate, sulfasalazine), or biologic DMARDs (e.g., inhibitors of TNF, IL-1, or IL-6) within the 3 months before knee IACI and during the follow-up period. * History of severe adverse reactions to steroids. * Presence of neurological diseases. * History of lower extremity surgery. * Missing data.

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Conditions

The condition(s) this trial relates to.

juvenile idiopathic arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Juvenile idiopathic arthritis (JIA)

Contacts and locations

Locations

  • Necmettin Erbakan University, Faculty of Health Sciences

    Konya, Turkey (Türkiye)

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