Steroid study reveals brain changes in just 3 days

NCT ID NCT03896659

First seen Jan 11, 2026 · Last updated Apr 25, 2026 · Updated 14 times

Summary

This study looked at how a 3-day course of hydrocortisone (a corticosteroid) affects memory and the hippocampus, a brain region key for learning. Researchers used advanced MRI scans and memory tests in 66 healthy adults and people with depression. The goal was to understand which parts of the hippocampus are most sensitive to steroids and whether depression changes the brain's response.

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Contacts and locations

Locations

  • UT Southwestern Medical Center

    Dallas, Texas, 75390, United States

Conditions

Explore the condition pages connected to this study.