Tiny lung sensor could keep heart failure patients out of the hospital

NCT ID NCT04089059

Ongoing Disease control Sponsor: Endotronix, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a small sensor placed in the lung artery to help doctors monitor heart failure patients remotely. 738 people with advanced (NYHA Class III) heart failure took part. The goal was to see if using the sensor could reduce hospitalizations and deaths compared to a target goal. The sensor sends pressure readings so doctors can adjust treatment early.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder heart disorder heart failure moderate heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE NYHA CLASS III

Contacts and locations

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Locations

Ascension Sacred Heart

Pensacola, Florida, 32504, United States
Ascension St Vincent's

Birmingham, Alabama, 35235, United States
Ascension St Vincent's

Indianapolis, Indiana, 46260, United States
Austin Heart

Austin, Texas, 78756, United States
Baptist Health South Florida

Miami, Florida, 33176, United States
Baylor - Round Rock

Round Rock, Texas, 78655, United States
Baylor - Temple

Temple, Texas, 76508, United States
Baylor/Texas Heart

Houston, Texas, 77030, United States
Beth Israel Deaconess Medical Center (BIDMC)

Boston, Massachusetts, 02215, United States
Brigham and Women's Hospital (Mass General Brigham)

Boston, Massachusetts, 02215, United States
Cardiovascular Center OLV Aalst

Aalst, Belgium
Centra Care Heart Center

Saint Cloud, Minnesota, 56303, United States
Cleveland Clinic

Weston, Florida, 33331, United States
Craig Cardiovascular Center

Gonzales, Texas, 78155, United States
Eisenhower Medical Center

Rancho Mirage, California, 92270, United States
Hackensack University Medical Center

Hackensack, New Jersey, 07601, United States
Hartford Hospital

Hartford, Connecticut, 06102, United States
Heart Centers of Illinois

Palos Park, Illinois, 60464, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Houston Methodist

Houston, Texas, 77030, United States
Huntsville Hospital

Huntsville, Alabama, 35801, United States
Kaiser San Francisco

San Francisco, California, 94118, United States
Kaiser Santa Clara

Santa Clara, California, 95051, United States
Loma Linda University

Loma Linda, California, 92354, United States
Medstar

Baltimore, Maryland, 21239, United States
Methodist Healthcare System

San Antonio, Texas, 78229, United States
Minneapolis Heart Institute Foundation

Minneapolis, Minnesota, 55407, United States
Mount Sinai

New York, New York, 10029, United States
NYU Langone Health

New York, New York, 11794, United States
New York Presbyterian Queens

Queens, New York, 11355, United States
Northwestern

Chicago, Illinois, 60611, United States
OSF Healthcare

Peoria, Illinois, 61107, United States
Ochsner Medical Center

New Orleans, Louisiana, 70121, United States
Ohio State University

Columbus, Ohio, 43210, United States
Oregon Health Science Portland

Portland, Oregon, 97239, United States
PRISMA Health- Upstate

Greenville, South Carolina, 29605, United States
PRISMA Midlands - Palmetto

Columbia, South Carolina, 29203, United States
Penn Medicine

Philadelphia, Pennsylvania, 19104, United States
Penn State Health

Hershey, Pennsylvania, 17033, United States
Phoenix Cardiovascular Research Group/Insight

Phoenix, Arizona, 85018, United States
Piedmont Athens

Athens, Georgia, 30600, United States
Providence Health Care

Spokane, Washington, 99204, United States
Queens Medical Center

Honolulu, Hawaii, 96813, United States
Sanford

Sioux Falls, South Dakota, 57105, United States
Sentara Healthcare

Norfolk, Virginia, 22191, United States
South Denver Cardiology

Littleton, Colorado, 80120, United States
St. Lukes/ Mid-American Heart Institute

Kansas City, Missouri, 64111, United States
Stony Brook University Med Center

Stony Brook, New York, 11794, United States
Tennova Healthcare (Turkey Creek Medical Center)

Knoxville, Tennessee, 37934, United States
The Valley Hospital

Ridgewood, New Jersey, 07450, United States
Thomas Jefferson

Philadelphia, Pennsylvania, 19107, United States
Thomas Jefferson Abington

Abington, Pennsylvania, 19001, United States
Tufts Medical Center

Boston, Massachusetts, 02111, United States
U of Chicago

Chicago, Illinois, 60637, United States
UCSD

San Diego, California, 92037, United States
UCSF Medical Center

San Francisco, California, 94143, United States
UPMC

Pittsburgh, Pennsylvania, 15213, United States
USF Health

Tampa, Florida, 33609, United States
University Hospital Galway

Galway, Ireland
University Of Louisville

Louisville, Kentucky, 40202, United States
University of Cincinnati

Cincinnati, Ohio, 45267, United States
University of Iowa Medical Center

Iowa City, Iowa, 52242, United States
University of Kansas Medical Center (KUMC)

Kansas City, Kansas, 66160, United States
University of Maryland

Baltimore, Maryland, 21201, United States
University of Minnesota

Minneapolis, Minnesota, 55455, United States
University of Texas/Hermann Memorial

Houston, Texas, 77030, United States
University of Vermont

Burlington, Vermont, 05401, United States
University of Washington

Seattle, Washington, 98196, United States
University of Wisconsin

Madison, Wisconsin, 53792, United States
Valley Health System/Winchester Medical Center

Winchester, Virginia, 22601, United States
Vanderbilt

Nashville, Tennessee, 37232, United States
West Virginia University

Morgantown, West Virginia, 26506, United States
ZNA Middlheim

Antwerp, Belgium
Ziekenhuis- Oost Limburg

Genk, Belgium