New nasal cannula could ease breathing for COPD patients

NCT ID NCT05829083

Recruiting now Symptom relief Sponsor: Larissa University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares a new asymmetric nasal cannula (DUET) to a standard one in 50 people with mild-to-moderate COPD flare-ups and high carbon dioxide levels. Each participant will try both devices for 3 hours to see which lowers CO2 better, reduces breathing effort, and feels more comfortable. The goal is to find a simpler way to help patients breathe easier and avoid more intensive treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Asymmetric nasal cannula (DUET device)
What this could lead to: If it works, this could offer a more effective way to help COPD patients breathe easier during flare-ups, potentially reducing the need for more intensive breathing support.
What could go wrong: This is a small, early crossover study with only 50 participants. The new cannula may not be more effective than the standard one, and some patients may find it uncomfortable or difficult to tolerate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset Hypercapnia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COPD COPD EXACERBATION HYPERCAPNIA

Contacts and locations

Locations

Sotiria General Hospital
RECRUITING

Athens, 11527, Greece
University Hospital of Larissa
RECRUITING

Larissa, 41110, Greece

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