Cold saline rinse after ERCP may prevent pancreatitis
NCT ID NCT07381478
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether rinsing the duodenal papilla with cold (3°C) sterile saline right after an ERCP procedure can lower the risk of post-ERCP pancreatitis. 900 adults in Colombia were randomly assigned to receive the cold saline rinse or standard care. The main goal was to see how many developed pancreatitis within 24 hours.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cold sterile saline (3°C)
What this could lead to
If it works, this simple cooling technique could become a standard way to prevent a common and painful complication of ERCP.
What could go wrong
This is a combined Phase 2/3 trial, so results are still preliminary. The cooling effect may not be strong enough to prevent pancreatitis, and there is a small risk of side effects like chills or minor bleeding.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospital San Rafael de Facatativá
Bogotá, Bogota D.C., 110111, Colombia