Can a smart patch predict dangerous immune reactions in cancer treatment?

NCT ID NCT07499128

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether a wearable patch called TempTraq can detect fevers earlier than standard temperature checks in cancer patients receiving immunotherapy. The goal is to see if continuous monitoring reduces the risk of severe cytokine release syndrome (CRS), a serious side effect. About 136 adults with cancer will wear the patch for up to 15 days while in the hospital. Some may also use a smartphone app to measure vital signs. The study is observational and does not provide a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
TempTraq wearable patch and VitalTraq app
What this could lead to
If successful, this could lead to earlier detection of fevers from cytokine release syndrome, potentially reducing severe complications in cancer patients receiving immunotherapy.
What could go wrong
This is an early-stage observational study with only 136 participants, so results may not apply to all patients. The patch monitors temperature but does not prevent CRS, and its benefit over standard care is unproven.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

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