New heart plug could free AF patients from lifelong blood thinners

NCT ID NCT03616028

Ongoing Disease control Sponsor: Conformal Medical, Inc Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new device called the Conformal Left Atrial Appendage Seal in 64 adults with non-valvular atrial fibrillation who are at high risk for stroke. The device is placed to close off a small pouch in the heart where blood clots can form, offering an alternative to long-term blood thinner medication. The main goals are to check safety and how well the device seals the pouch.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-VALVULAR ATRIAL FIBRILLATION

Contacts and locations

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Locations

Baylor Scott & white Research Institute

Plano, Texas, 75093, United States
Catholic Medical Center

Manchester, New Hampshire, 03102, United States
Columbia University Medical Center/NYPH

New York, New York, 10032, United States
Erlanger Health System

Chattanooga, Tennessee, 37403, United States
Lankenau Heart Institute

Wynnewood, Pennsylvania, 19096, United States
Mount Sinai

New York, New York, 10029, United States
Pacific Heart Institute

Santa Monica, California, 90404, United States
St. Bernards Medical Center

Jonesboro, Arkansas, 72401, United States
Texas Cardiac Arrhythmia Institute

Austin, Texas, 78705, United States
The Christ Hospital

Cincinnati, Ohio, 45219, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States

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