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Titanium versus Nano-Carbon CAD/CAM frameworks for All-on-4 implant supported hybrid prosthesis. a study of peri-implant tissue changes and prosthetic complications

NCT ID NCT07812363

NEW Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 10, 2026 · Last updated Sep 10, 2026

Summary

This clinical study compares two CAD/CAM framework materials, titanium and nano-carbon fiber-reinforced composite, used in mandibular All-on-4 implant-supported hybrid prostheses. Ten completely edentulous patients are randomly allocated into two equal groups. The study evaluates peri-implant soft tissue health, changes in marginal bone levels,and prosthetic complications over an 12-month follow-up period.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

10 people

The number who actually took part.

Started

May 2024

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \* Completely edentulous patients requiring mandibular implant-supported rehabilitation. * Adequate bone quantity and quality in the mandibular interforaminal region for implant placement. * Adequate restorative space for an implant-supported hybrid prosthesis. * Healthy oral mucosa and acceptable oral hygiene. * Patients medically fit to undergo implant surgery. * Ability and willingness to attend the scheduled follow-up visits and provide informed consent. Exclusion Criteria: * Systemic conditions or medical contraindications that could interfere with implant surgery or healing. * History of radiotherapy to the head and neck region. * Smoking. * Alcohol abuse. * Bruxism or clenching habits. * Any local condition that could compromise implant placement or the planned prosthetic rehabilitation.

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Conditions

The condition(s) this trial relates to.

anodontia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Complete edentulism

Contacts and locations

Locations

  • Faculty of Dentistry, Mansoura University

    Al Mansurah, Dakahlia Governorate, Egypt

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