Last-Resort drug linvoseltamab offered to myeloma patients with no other options

NCT ID NCT05164250

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This program provides linvoseltamab (REGN5458) to patients with relapsed or refractory multiple myeloma who have exhausted all standard treatments. The drug is a type of immunotherapy that helps the immune system attack cancer cells. It is given through compassionate use, meaning it is available outside of a clinical trial for those with no alternatives.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

linvoseltamab (REGN5458)

What this could lead to

If this treatment works, it could offer a new option for patients with multiple myeloma that has stopped responding to other therapies.

What could go wrong

This is a compassionate use program, not a formal trial, so data on safety and effectiveness is limited. The drug may not work for everyone and can cause serious side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.