Could a gentler surgery be just as effective for aggressive uterine cancer?

This study compares two surgical approaches for people with early-stage, high-risk endometrial cancer that has a p53 mutation. One group will have a standard surgery that removes many lymph nodes, while the other will have a less invasive procedure that only removes a few key lymph nodes (sentinel nodes). The goal is to see if the gentler approach works just as well at preventing cancer from coming back, while causing fewer side effects. About 374 participants will be followed for three years to measure cancer recurrence, survival, and quality of life.