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Can a breathing test personalize nutrition for cancer patients?

NCT ID NCT07776704

Disease control Sponsor: Fox Chase Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This trial asks whether using a device that measures a person's actual energy needs (indirect calorimetry) is a better way to prescribe parenteral nutrition—liquid food given through a vein—for adults with cancer who cannot eat enough by mouth. Half of the participants will have their nutrition dose based on this measured energy expenditure, while the other half will receive a standard dose based on body weight. The study will see if the measuring approach is practical and acceptable to patients over an 8-week period.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Indirect calorimetry (a device that measures energy expenditure) and weight-based parenteral nutrition dosing
What this could lead to
If successful, this could lead to more personalized and accurate nutrition dosing for cancer patients who cannot eat normally, potentially improving their nutritional status and overall well-being.
What could go wrong
This is a small, early-stage feasibility study, so results may not be conclusive. The indirect calorimetry device may be uncomfortable or impractical for some patients, and the study does not yet measure long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Jan 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged ≥18 years * Diagnosis of cancer * Requirement for PN ≥1 week * Ability to provide informed consent * English-speaking Exclusion Criteria: * Hospice enrollment * Mechanical ventilation * Chest tube or drain * Continuous renal replacement therapy * Supplemental oxygen

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Conditions

The condition(s) this trial relates to.

cancer Hyperphagia neoplasm nutritional deficiency disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer Malnutitrion

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Fox Chase Cancer Center

    RECRUITING

    Philadelphia, Pennsylvania, 19111, United States

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