Stomach cancer surgery showdown: which operation saves more lives?

NCT ID NCT07482566

Recruiting now Knowledge-focused Sponsor: Nurettin Şahin Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two surgical procedures for patients with a specific type of cancer where the stomach meets the esophagus. Half of the 120 participants will have only the upper part of the stomach removed (proximal gastrectomy), while the other half will have the entire stomach removed (total gastrectomy). Researchers will track who lives longer without the cancer coming back over three years, and also monitor complications and recovery. The goal is to find out if the less extensive surgery is just as safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If this trial succeeds, it could show that a less extensive surgery (proximal gastrectomy) is as effective as total stomach removal, potentially improving quality of life for patients.
What could go wrong: This is a surgical comparison study, not a test of a new drug or cure. Results may not apply to all patients, and both surgeries carry risks like infection or leakage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Esophageal Neoplasms gastric neoplasm gastroesophageal cancer gastroesophageal junction adenocarcinoma neoplasm of esophagus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ESOPHAGEAL NEOPLASMS GASTROESOPHAGEAL JUNCTION CANCER STOMACH NEOPLASMS

Contacts and locations

Locations

Bakirkoy Dr. Sadi Konuk Training and Research Hospital
RECRUITING

Istanbul, Istanbul, 34147, Turkey (Türkiye)

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