Stomach cancer surgery showdown: which operation saves more lives?

NCT ID NCT07482566

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two surgical procedures for patients with a specific type of cancer where the stomach meets the esophagus. Half of the 120 participants will have only the upper part of the stomach removed (proximal gastrectomy), while the other half will have the entire stomach removed (total gastrectomy). Researchers will track who lives longer without the cancer coming back over three years, and also monitor complications and recovery. The goal is to find out if the less extensive surgery is just as safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If this trial succeeds, it could show that a less extensive surgery (proximal gastrectomy) is as effective as total stomach removal, potentially improving quality of life for patients.

What could go wrong

This is a surgical comparison study, not a test of a new drug or cure. Results may not apply to all patients, and both surgeries carry risks like infection or leakage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Esophageal Neoplasms gastric neoplasm gastroesophageal cancer gastroesophageal junction adenocarcinoma neoplasm of esophagus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bakirkoy Dr. Sadi Konuk Training and Research Hospital

    RECRUITING

    Istanbul, Istanbul, 34147, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••