Shorter light therapy may be just as good for treating bulging corneas
NCT ID NCT07124910
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This phase 3 trial tests whether a shorter 18-minute ultraviolet (UVA) light exposure works as well as the standard 24-minute exposure during corneal crosslinking for keratoconus and similar conditions. The treatment uses riboflavin (vitamin B2) eye drops followed by UVA light to strengthen the cornea and stop vision loss. About 485 participants aged 8 and older will be followed for 6 months to compare changes in corneal shape and eyesight between the two groups.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
riboflavin (vitamin B2) eye drops plus ultraviolet (UVA) light
What this could lead to
If it works, this could show that a shorter 18-minute UVA exposure is just as effective as the standard 24-minute one, making treatment faster and more comfortable.
What could go wrong
This is still an experimental treatment not yet FDA-approved. The trial is relatively small and only follows participants for 6 months, so long-term benefits and risks are unknown.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Woolfson Eye Institute
RECRUITINGAtlanta, Georgia, 30328, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Woolfson Eye Institute
RECRUITINGAtlanta, Georgia, 30349, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Woolfson Eye Institute
RECRUITINGCanton, Georgia, 30114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Woolfson Eye Institute
RECRUITINGCumming, Georgia, 30041, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Woolfson Eye Institute
RECRUITINGDouglasville, Georgia, 30134, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Woolfson Eye Institute
RECRUITINGLawrenceville, Georgia, 30043, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Woolfson Eye Institute
RECRUITINGMarietta, Georgia, 30066, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Woolfson Eye Institute
RECRUITINGSnellville, Georgia, 30078, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Woolfson Eye Institute
RECRUITINGAsheville, North Carolina, 28803, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Woolfson Eye Institute
RECRUITINGChattanooga, Tennessee, 37421, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Woolfson Eye Institute
RECRUITINGJohnson City, Tennessee, 37615, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Woolfson Eye Institute
RECRUITINGKnoxville, Tennessee, 37922, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••