Which chemo works best for esophageal cancer? new trial aims to find out
NCT ID NCT02359968
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compared two chemotherapy regimens (FOLFOX and CarboP-pacliT) given with radiation before surgery for esophageal or junction cancer. 106 patients were enrolled to see which treatment leads to better tumor removal and fewer serious complications. The goal is to help doctors choose the best approach for this type of cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
FOLFOX (fluorouracil, oxaliplatin, folinic acid) and CarboP-pacliT (carboplatin, paclitaxel)
What this could lead to
If this trial succeeds, it could show which chemotherapy combination works best before surgery for esophageal cancer, helping doctors choose the most effective treatment.
What could go wrong
This is a phase 2 trial with only 106 participants, so results may not apply to everyone. Both treatments have side effects, and the study may not find a clear winner.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CH Lyon sud
Pierre-Bénite, France
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CHU Bordeaux
Bordeaux, France
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Centre Eugène Marquis
Rennes, France
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Centre Oscar Lambret
Lille, 59020, France
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Hôpital La Timone
Marseille, France
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Hôpital Nord
Marseille, France
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ICM - Val d'Aurelle
Montpellier, France
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ICO Paul Papin
Angers, France
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ICO René Gauducheau
Saint-Herblain, France
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University Hospital of Lille
Lille, 59000, France