Which chemo combo works best for esophageal cancer? new trial aims to find out

NCT ID NCT02359968

First seen Mar 24, 2026 · Last updated May 15, 2026 · Updated 9 times

Summary

This study compared two different chemotherapy combinations given with radiation before surgery for people with esophageal or junction cancer. The goal was to see which treatment leads to better tumor removal and fewer serious side effects after surgery. 106 participants were randomly assigned to receive either the standard FOLFOX regimen or a paclitaxel-carboplatin combo.

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Contacts and locations

Locations

  • CH Lyon sud

    Pierre-Bénite, France

  • CHU Bordeaux

    Bordeaux, France

  • Centre Eugène Marquis

    Rennes, France

  • Centre Oscar Lambret

    Lille, 59020, France

  • Hôpital La Timone

    Marseille, France

  • Hôpital Nord

    Marseille, France

  • ICM - Val d'Aurelle

    Montpellier, France

  • ICO Paul Papin

    Angers, France

  • ICO René Gauducheau

    Saint-Herblain, France

  • University Hospital of Lille

    Lille, 59000, France

Conditions

Explore the condition pages connected to this study.