New study tests best method to quit antidepressants without relapse

NCT ID NCT07393919

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study compares two strategies for safely stopping antidepressants in adults whose depression is in remission. Participants will be randomly assigned to either a standard gradual dose reduction or a more precise hyperbolic tapering method. The goal is to see which approach leads to more successful discontinuation with fewer withdrawal symptoms or relapse over 36 weeks.

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