New hope for Drug-Resistant lung cancer: triple therapy shows promise in early trial

NCT ID NCT04285671

First seen Mar 10, 2026 · Last updated Jun 10, 2026 · Updated 13 times

Summary

This study tests a combination of three drugs—osimertinib, trastuzumab, and necitumumab—in people with advanced EGFR-mutated lung cancer that no longer responds to osimertinib alone. About 30 participants will receive the drugs to find the safest dose and see if the combination can shrink tumors. The goal is to control the cancer, not cure it, as ongoing treatment is needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • UCLA / Jonsson Comprehensive Cancer Center

    Los Angeles, California, 90095, United States

Conditions

Explore the condition pages connected to this study.