New hope for aggressive brain cancer: radiation plus immunotherapy shows promise

NCT ID NCT02866747

First seen Apr 20, 2026 · Last updated Apr 28, 2026 · Updated 2 times

Summary

This study tested whether adding an immunotherapy drug (durvalumab) to targeted radiation therapy can help people with recurrent glioblastoma, an aggressive brain cancer. About 108 adults whose cancer returned after previous treatments took part. The goal was to see if the combination improves survival and controls tumor growth better than radiation alone.

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Contacts and locations

Locations

  • Centre Francois Baclesse

    Caen, 14 000, France

  • Centre Georges Francois Leclerc

    Dijon, 21 000, France

  • Centre Paul Strauss

    Strasbourg, 67000, France

  • Hopital Avicenne

    Bobigny, 93 000, France

  • Hopital Pitie Salpetriere

    Paris, 75013, France

  • Institut Claudius Regaud

    Toulouse, France

  • Institut Curie

    Saint-Cloud, 92 210, France

  • Institut Gustave Roussy

    Villejuif, 94 800, France

  • Institut Regional Du Cancer de Montpellier

    Montpellier, 34 298, France

  • Institut de Cancerologie de L'Ouest

    Angers, 49055, France

Conditions

Explore the condition pages connected to this study.