New triple therapy takes on tough colorectal cancer
NCT ID NCT07550088
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase II trial tests whether a combination of three drugs—balstilimab, botensilimab, and agenT-797—can shrink tumors in adults with a specific type of advanced colorectal cancer that has spread to the liver. All 17 participants will receive the treatment, and researchers will track tumor response and side effects. The goal is to find a new option for patients who have already tried standard chemotherapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
balstilimab, botensilimab, and agenT-797 (a type of immune cell therapy)
What this could lead to
If this works, it could offer a new treatment option for people with a hard-to-treat form of colorectal cancer that has spread to the liver.
What could go wrong
This is a small, early-phase trial with only 17 participants and no comparison group. The combination may cause significant side effects, including immune reactions, and may not shrink tumors in most patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Scripps Clinic Torrey Pines
La Jolla, California, 92037, United States
Contact Email: •••••@•••••