New combo therapy targets Hard-to-Treat cancers
NCT ID NCT05694715
First seen Mar 21, 2026 · Last updated May 16, 2026 · Updated 5 times
Summary
This early-stage trial tests a combination of two drugs, niraparib and irinotecan, in people with advanced solid tumors that have mutations in DNA repair genes like BRCA, ATM, or PALB2. The main goal is to find a safe dose and understand side effects. About 24 adults with cancers such as breast, ovarian, pancreatic, or colon cancer will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94143, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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