Flu drug cocktail shows promise in hospitalized patients

NCT ID NCT04327791

Completed Disease control Sponsor: Bassett Healthcare Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 2/3 trial tested whether adding baloxavir to standard oseltamivir treatment helps hospitalized flu patients clear the virus faster. Fifteen adults with confirmed influenza were randomly assigned to receive either the combination or oseltamivir alone. The main goal was to measure how quickly the virus disappeared from nasal swabs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: baloxavir and oseltamivir
What this could lead to: If it works, this combination could help hospitalized flu patients clear the virus faster and reduce complications.
What could go wrong: This was a very small early-stage trial with only 15 participants, so results may not apply broadly. The combination also carries unknown risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for INFLUENZA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

influenza

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFLUENZA

Contacts and locations

Locations

Bassett Medical Center

Cooperstown, New York, 13326, United States
Baystate Medical Center

Springfield, Massachusetts, 01199, United States
Oregon Health & Science University

Portland, Oregon, 97239, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.