New device aims to spare rectal cancer patients from stoma surgery

NCT ID NCT07429110

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a device called ColoSeal ICD, placed during rectal cancer surgery to protect the bowel connection and reduce the need for a stoma (a bag on the belly for waste). About 250 adults aged 22-75 with rectal cancer will be split into two groups: one gets the device, the other gets standard care with a stoma. Researchers will compare major complications and how many people avoid a stoma after 30 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ColoSeal ICD System (a medical device placed during surgery to protect the bowel connection)

What this could lead to

If it works, this device could help many rectal cancer patients avoid a temporary or permanent stoma after surgery, improving quality of life.

What could go wrong

This is a pivotal study but not yet recruiting, so results are unknown. The device may not reduce stoma rates or could cause complications like infection or leakage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medical University of South Carolina

    Charleston, South Carolina, 29402, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Utah Health

    Salt Lake City, Utah, 84132, United States

    Contact

    Contact Email: •••••@•••••