AI-Designed cancer vaccine enters human testing for colorectal cancer

NCT ID NCT07328087

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tests a personalized vaccine called COLONYVAQ-CRC, designed using AI and quantum physics, for patients with stage III colorectal cancer that has been surgically removed. The vaccine is given alongside standard chemotherapy and an immunotherapy drug (nivolumab). The main goal is to check safety and side effects in 12 to 50 participants. Researchers will also look at immune responses and whether the vaccine helps keep cancer from coming back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

personalized neoantigen peptide vaccine (COLONYVAQ-CRC)

What this could lead to

If successful, this could lead to a new personalized vaccine approach to help prevent colorectal cancer from returning after surgery.

What could go wrong

This is a very early, small trial (12-50 people) focused on safety. The vaccine is custom-made for each patient, which is complex and may not work for everyone. Side effects from the combination treatment are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Biogenea Pharmaeuticals Ltd

    RECRUITING

    Thessaloniki, 54627, Greece