AI-Designed cancer vaccine enters human testing for colorectal cancer
NCT ID NCT07328087
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tests a personalized vaccine called COLONYVAQ-CRC, designed using AI and quantum physics, for patients with stage III colorectal cancer that has been surgically removed. The vaccine is given alongside standard chemotherapy and an immunotherapy drug (nivolumab). The main goal is to check safety and side effects in 12 to 50 participants. Researchers will also look at immune responses and whether the vaccine helps keep cancer from coming back.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- personalized neoantigen peptide vaccine (COLONYVAQ-CRC)
- What this could lead to
- If successful, this could lead to a new personalized vaccine approach to help prevent colorectal cancer from returning after surgery.
- What could go wrong
- This is a very early, small trial (12-50 people) focused on safety. The vaccine is custom-made for each patient, which is complex and may not work for everyone. Side effects from the combination treatment are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Biogenea Pharmaeuticals Ltd
RECRUITINGThessaloniki, 54627, Greece
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can two immune boosters outsmart Chemo-Resistant colon cancer?
- Could a liver transplant from a living donor help fight colorectal cancer that spread?