Can a collagen patch save your jawbone after a tooth pull?
NCT ID NCT07270510
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether placing a collagen matrix into the tooth socket right after extraction helps preserve bone and gum tissue better than letting the socket heal on its own. Twenty-four healthy adults with a single non-molar tooth that cannot be saved will be randomly assigned to either extraction alone or extraction plus the collagen graft. Researchers will compare changes in bone height and width, as well as gum thickness, using 3D scans taken right after surgery and again three months later.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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24 people
The number who actually took part.
- Started
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Jul 2025
- Expected to finish
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Feb 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy adults (absence of cardiovascular diseases, thyroid diseases, oncological diseases Non-smokers Extraction diagnosis on non-molar teeth Gingivitis, stage 1-2 periodontitis conditions Absence of radiotherapy last 2 years Non restorable teeth (deep fracture, excessive caries, failed root canal treatment) Overall plaque score and gingival score of \<10% Exclusion Criteria: Systemically compromised patients Smokers Pregnancy or lactation Heavy periodontally compromised patients (Stage 3-4) Patients undergone radiotherapy in the last 2 years Collagen allergic patients Restorable teeth Overall plaque score and gingival score of \>10%
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Altinbas University
Istanbul, Istanbul, 34147, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Which bone graft works best for saving your jawbone after a tooth pull?