Could a cold rinse soothe radiation mouth sores?
NCT ID NCT07252557
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will test whether rinsing with cold water (15-20°C) reduces mouth soreness and improves comfort compared to room-temperature water in 200 head and neck cancer patients undergoing radiotherapy. Participants will rinse four times daily for six weeks. The goal is to see if cold water can lessen pain and prevent treatment delays.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
water rinse at different temperatures (cold vs. room-temperature)
What this could lead to
If cold rinses work, patients could have less mouth pain and fewer treatment breaks during radiotherapy.
What could go wrong
This is a small, early-stage trial with no blinding, so results may be influenced by patient expectations. The effect may be modest.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Chung Shan Medical University
Taichung, Taiwan (r.o.c.), Taiwan