Could a cold rinse soothe radiation mouth sores?
NCT ID NCT07252557
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will test whether rinsing with cold water (15-20°C) reduces mouth soreness and improves comfort compared to room-temperature water in 200 head and neck cancer patients undergoing radiotherapy. Participants will rinse four times daily for six weeks. The goal is to see if cold water can lessen pain and prevent treatment delays.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- water rinse at different temperatures (cold vs. room-temperature)
- What this could lead to
- If cold rinses work, patients could have less mouth pain and fewer treatment breaks during radiotherapy.
- What could go wrong
- This is a small, early-stage trial with no blinding, so results may be influenced by patient expectations. The effect may be modest.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Chung Shan Medical University
Taichung, Taiwan (r.o.c.), Taiwan
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