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Common drug could be Game-Changer for millions with clogged leg arteries

NCT ID NCT04774159

Recruiting now Disease control Sponsor: Population Health Research Institute Source: ClinicalTrials.gov ↗

Summary

This large, late-stage trial is testing whether a low daily dose of an existing anti-inflammatory drug (colchicine) can prevent serious complications in people with symptomatic peripheral artery disease (PAD). It aims to see if the drug reduces the combined risk of heart attacks, strokes, cardiovascular death, and severe limb problems requiring surgery or amputation. The study will enroll over 6,000 participants who have leg pain when walking or more severe circulation issues.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

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    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bradford Teaching Hospital

    RECRUITING

    Bradford, United Kingdom

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  • CIUSSS du Nord-de-l'île-de-Montréal, Hôpital du Sacré-Cœur-de-Montréal

    RECRUITING

    Montreal, Quebec, Canada

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  • CPTEM - Centro de Pesquisa e Tecnologia Multidisciplinar

    RECRUITING

    São Paulo, Brazil

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  • Cardiolife

    RECRUITING

    Quito, Pichincha, Ecuador

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  • Centre intégré de santé et de services sociaux du Bas-Saint-Laurent

    RECRUITING

    Rimouski, Quebec, G5L 3N2, Canada

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  • Clínica Procárdio

    RECRUITING

    Blumenau, Santa Catarina, Brazil

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  • Corcare Cardiovascular Research Inc.

    RECRUITING

    Scarborough Village, Ontario, Canada

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  • Derriford Hospital

    RECRUITING

    Plymouth, England, United Kingdom

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  • Duke Raleigh Hospital

    RECRUITING

    Raleigh, North Carolina, 27609, United States

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  • Duke Regional Hospital

    RECRUITING

    Durham, North Carolina, 27704, United States

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  • Duke University Medical Center

    RECRUITING

    Durham, North Carolina, 27710, United States

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  • Glenfield Hospital

    RECRUITING

    Leicester, United Kingdom

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  • HFR Fribourg

    RECRUITING

    Fribourg, Switzerland

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  • Hamilton General Hospital

    RECRUITING

    Hamilton, Ontario, L8L 2X2, Canada

    Contact Phone: •••-•••-••••

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  • Henry Ford Health System

    RECRUITING

    Detroit, Michigan, 48202, United States

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  • Hospital Alemão Oswaldo Cruz

    RECRUITING

    São Paulo, Brazil

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  • Hospital Carlos Fernando Malzoni

    RECRUITING

    Matão, Brazil

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  • Hospital Universitário (CoraCentro Pesquisa Clinica)

    RECRUITING

    Canoas, Brazil

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  • Hospital de Especialidades de las Fuerzas Armadas N 1

    RECRUITING

    Quito, Pichincha, Ecuador

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  • Hull Royal Infirmary

    RECRUITING

    Hull, United Kingdom

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  • Hôpitaux Universitaires de Genève

    RECRUITING

    Geneva, Switzerland

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  • Incore

    RECRUITING

    Dois Vizinhos, Brazil

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  • Instituto de Cardiologia do Rio Grande do Sul

    RECRUITING

    Porto Alegre, Brazil

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  • Kent and Canterbury Hospital

    RECRUITING

    Canterbury, England, United Kingdom

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  • London Health Sciences Centre

    RECRUITING

    London, Ontario, Canada

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  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

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  • Niagara Health System

    RECRUITING

    St. Catharines, Ontario, Canada

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  • Ohio State University Wexner Medical Center

    RECRUITING

    Columbus, Ohio, 43210, United States

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  • Ospedale Regionale Bellinzona e Valli - Ente Ospedaliero Cantonale

    RECRUITING

    Bellinzona, Switzerland

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  • Pinderfields Hospital

    RECRUITING

    Wakefield, England, United Kingdom

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  • Royal Infirmary Edinburgh

    RECRUITING

    Edinburgh, Scotland, United Kingdom

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  • Royal Sussex County Hospital

    RECRUITING

    Brighton, England, United Kingdom

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  • Rutgers University

    RECRUITING

    Newark, New Jersey, 07103, United States

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  • Santa Casa de Misericórdia de Ponta Grossa

    RECRUITING

    Ponta Grossa, Brazil

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  • Sociedade Hospitalar Angelina Caron

    RECRUITING

    Campina Grande do Sul, Brazil

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  • Southmead Hospital

    RECRUITING

    Bristol, England, United Kingdom

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  • Southwest Family Medicine

    RECRUITING

    Dallas, Texas, 75235, United States

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  • St. George's University Hospitals

    RECRUITING

    London, United Kingdom

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  • Sunnybrook Research Institute

    RECRUITING

    Toronto, Ontario, Canada

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  • Tampa General Hospital

    RECRUITING

    Tampa, Florida, 33606, United States

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  • Texas Tech University Health Sciences

    RECRUITING

    Lubbock, Texas, 79430, United States

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  • The Leeds Teaching Hospital

    RECRUITING

    Leeds, United Kingdom

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  • Toronto General Hospital

    RECRUITING

    Toronto, Ontario, Canada

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  • UniCarMeDr.D

    RECRUITING

    Quito, Pichincha, Ecuador

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  • Universitair Ziekenhuis Leuven

    RECRUITING

    Leuven, Belgium

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  • University Hospital Basel, Angiology

    RECRUITING

    Basel, Switzerland

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  • University Hospital Zurich, Clinic of Angiology

    RECRUITING

    Zurich, Switzerland

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  • University Medical Center Utrecht

    RECRUITING

    Utrecht, Netherlands

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  • University of Alberta, Mazankowski Heart Institute

    RECRUITING

    Edmonton, Alberta, Canada

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  • University of Calgary, Peter Lougheed Centre Vascular Clinic

    RECRUITING

    Calgary, Alberta, Canada

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  • University of Chicago Medical Center

    RECRUITING

    Chicago, Illinois, 60615, United States

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  • University of Florida - Gainesville

    RECRUITING

    Gainesville, Florida, 32611, United States

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  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

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  • University of Texas Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

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  • University of Washington Medical Center

    RECRUITING

    Seattle, Washington, 98195, United States

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  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

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  • Vascular Health Bronte

    RECRUITING

    Oakville, Ontario, Canada

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  • Via Medica

    RECRUITING

    Goiânia, Brazil

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  • Yale School of Medicine

    RECRUITING

    New Haven, Connecticut, 06511, United States

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Conditions

Explore the condition pages connected to this study.

ATHEROSCLEROSIS OF EXTREMITIES INFLAMMATION PERIPHERAL ARTERIAL DISEASE