Old drug, new trick: colchicine may shield hearts during surgery

NCT ID NCT05618353

Recruiting now Disease control Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether colchicine, an inexpensive anti-inflammatory drug used for gout, can prevent heart attacks, strokes, and death in heart disease patients undergoing major surgery. Researchers will give the drug to 700 veterans before and after their operation. The goal is to see if calming inflammation can lower the risk of serious heart complications.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder Inflammation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE

Contacts and locations

Locations

Birmingham VA Medical Center, Birmingham, AL
RECRUITING

Birmingham, Alabama, 35233-1927, United States
Durham VA Medical Center, Durham, NC
RECRUITING

Durham, North Carolina, 27705-3875, United States
Louis Stokes VA Medical Center, Cleveland, OH
RECRUITING

Cleveland, Ohio, 44106-1702, United States
Michael E. DeBakey VA Medical Center, Houston, TX
RECRUITING

Houston, Texas, 77030-4211, United States
North Florida/South Georgia Veterans Health System, Gainesville, FL
RECRUITING

Gainesville, Florida, 32608-1135, United States
VA Long Beach Healthcare System, Long Beach, CA
RECRUITING

Long Beach, California, 90822, United States
VA NY Harbor Healthcare System, New York, NY
RECRUITING

New York, New York, 10010-5011, United States
VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX
RECRUITING

Dallas, Texas, 75216-7167, United States
VA Western New York Healthcare System, Buffalo, NY
RECRUITING

Buffalo, New York, 14215-1129, United States

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