Can an online brain workout sharpen thinking in multiple sclerosis?

NCT ID NCT07734675

Not yet recruiting Disease control Sponsor: Sonia Batista Source: ClinicalTrials.gov ↗

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This trial tests whether a year-long, home-based cognitive training program can improve memory, attention, and emotional understanding in people with multiple sclerosis. Participants use the COGWEB platform plus exercises for recognizing facial expressions, with most sessions done online. The goal is to see if this approach can boost cognitive reserve and slow mental decline.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: a sociocognitive rehabilitation program using the COGWEB platform combined with emotional processing training
What this could lead to: If effective, this program could offer a practical, home-based way to slow or improve cognitive decline in people with multiple sclerosis.
What could go wrong: This is a single-center trial with 130 participants, so results may not apply broadly. The intervention requires consistent engagement over 12 months, and cognitive improvements may be modest or short-lived.

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Conditions

The condition(s) this trial relates to.

autoimmune disease Cognitive Dysfunction multiple sclerosis relapsing-remitting multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE SCLEROSIS

Contacts and locations

Locations

Local Health Unit of Coimbra

Coimbra, Coimbra District, 3004-561, Portugal
Unidade Local de Saude de Coimbra

Coimbra, Coimbra District, Portugal

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