New hope for brain fog in schizophrenia: drug trial targets memory and focus

NCT ID NCT07191483

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 33 times

Summary

This study tests an experimental drug called KYN-5356 to see if it can help with thinking and memory problems that often come with schizophrenia. About 150 adults with stable schizophrenia will take either a low, medium, or high dose of the drug or a placebo daily for 28 days while staying in a clinic. Researchers will measure changes in cognitive function using a digital test and check safety and drug levels in the body.

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Contacts and locations

Locations

  • Arch Clinical Trials

    RECRUITING

    St Louis, Missouri, 63125, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cenexel ACMR

    RECRUITING

    Atlanta, Georgia, 30331, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cenexel CBH

    RECRUITING

    Gaithersburg, Maryland, 20877, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cenexel CNS

    RECRUITING

    Los Alamitos, California, 90720, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cenexel HRI

    RECRUITING

    Marlton, New Jersey, 08053, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cenexel RCA

    RECRUITING

    Hollywood, Florida, 33024, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cenexel iResearch Atlanta

    RECRUITING

    Decatur, Georgia, 30030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Community Clinical Research

    RECRUITING

    Austin, Texas, 78754, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Neuro-Behavioral Clinical Research

    RECRUITING

    North Canton, Ohio, 44720, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Segal Trials

    RECRUITING

    Miami Lakes, Florida, 33016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Synergy Research Center

    RECRUITING

    Lemon Grove, California, 92064, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Uptown Research Institute

    RECRUITING

    Chicago, Illinois, 60640, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Woodland International Research Group

    RECRUITING

    Little Rock, Arkansas, 72211, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.