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Brain resilience in bipolar disorder: what protects thinking skills?

NCT ID NCT04454073

Knowledge-focused Sponsor: St. Olavs Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study looks at why about 30-50% of people with bipolar disorder have normal thinking abilities, while others struggle. Researchers will test memory, attention, and problem-solving skills in 87 adults with stable mood. They will also examine sleep, weight, daily routines, and other health factors to find what helps preserve brain function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could identify factors that protect thinking abilities in people with bipolar disorder, pointing toward ways to preserve cognitive health.
What could go wrong
This is an observational study, not a treatment trial. It may find associations but cannot prove cause and effect. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

87 people

The number who actually took part.

Started

Oct 2021

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Bipolar patients diagnosed with Bipolar disorder I or II, in euthymic state or with mild to moderate symptoms at time of assessment.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individuals aged \>=18 years who score \<= 16 on the MADRS or \<= 8 on the YMRS. * Willing and able to give online informed consent. Exclusion Criteria: * Symptom level above inclusion criteria will be put on a waiting list, and if informed consent is given, will be included when symptom level is reduced. * No Norwegian fluency.

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Conditions

The condition(s) this trial relates to.

bipolar disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bipolar disorder

Contacts and locations

Locations

  • Bipolar and sleep outpatient clinic, Department of Østmarka, Division of Mental Health Care

    Trondheim, Norway

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