New combo procedure aims to fix heart rhythm and prevent stroke in one go
NCT ID NCT07450755
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will test a combined procedure in 150 people with atrial fibrillation (AFib) who are at risk for stroke. Doctors will use pulse field ablation to correct the heart's rhythm and then close off a small pouch in the heart (the left atrial appendage) to prevent blood clots. The goal is to see if doing both at once is safe and effective, potentially reducing the need for long-term blood thinners.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pulse field ablation and left atrial appendage closure devices (Farapulse, Watchman Flx)
What this could lead to
If successful, this combined procedure could offer a one-time treatment to control atrial fibrillation and reduce stroke risk, potentially lowering the need for long-term blood thinners.
What could go wrong
This is an early-stage registry with no control group, so results may not prove superiority over standard care. Risks include procedure-related complications like bleeding, stroke, or heart damage.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for STROKE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••