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New vaccine aims to shield stem cell patients from dangerous virus

NCT ID NCT07020533

Recruiting now Prevention Sponsor: City of Hope Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This early-phase trial tests a vaccine (CMV-MVA Triplex) given to both stem cell donors and recipients to boost immunity against cytomegalovirus (CMV) and prevent active infection after a half-matched stem cell transplant. About 46 people with various blood cancers will take part. The goal is to see if the vaccine is safe and helps reduce CMV-related complications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia acute myeloid leukemia B-cell chronic lymphocytic leukemia chronic myelogenous leukemia, BCR-ABL1 positive hematopoietic and lymphoid system neoplasm Hodgkins lymphoma leukemia, myeloid, accelerated-phase Leukemia, Myeloid, Chronic-Phase lymphoblastic lymphoma myelodysplastic syndrome Myelodysplastic Syndromes myelofibrosis Myeloproliferative Disorders myeloproliferative neoplasm non-Hodgkin lymphoma Precursor Cell Lymphoblastic Leukemia-Lymphoma primary myelofibrosis cytomegalovirus infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACCELERATED PHASE CHRONIC MYELOID LEUKEMIA, BCR-ABL1 POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA ACUTE MYELOID LEUKEMIA CHRONIC LYMPHOCYTIC LEUKEMIA CHRONIC PHASE CHRONIC MYELOID LEUKEMIA, BCR-ABL1 POSITIVE HEMATOPOIETIC AND LYMPHATIC SYSTEM NEOPLASM HODGKIN LYMPHOMA LYMPHOBLASTIC LYMPHOMA MYELODYSPLASTIC SYNDROME MYELOFIBROSIS MYELOPROLIFERATIVE NEOPLASM NON HODGKIN LYMPHOMA

Contacts and locations

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Northside Hospital

    RECRUITING

    Atlanta, Georgia, 30342, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact