New study aims to stop CMV in kidney transplants

NCT ID NCT07203664

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two different drug combinations to prevent cytomegalovirus (CMV) infection in kidney transplant patients who are at high risk. Thirty adults who are CMV-positive before transplant will receive either tacrolimus plus mTOR inhibitors with early antiviral treatment, or tacrolimus plus mycophenolic acid with standard preventive antivirals. The goal is to see which strategy better prevents CMV disease and monitors immune response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tacrolimus, mTOR inhibitors, mycophenolic acid, valganciclovir

What this could lead to

If successful, this could point toward a more effective CMV prevention strategy for kidney transplant patients, reducing infection and complications.

What could go wrong

This is a small, early-phase trial with only 30 participants, so results may not apply to all patients. The study is not yet recruiting, and the interventions carry risks like infection or organ rejection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

end stage renal failure cytomegalovirus infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital Universitario La Paz, Pº de la Castellana, 261 (Servicio de Nefrologia)

    Madrid, Madrid, 28046, Spain