Blood thinner clopidogrel fails many seniors – study seeks answers
NCT ID NCT04990596
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study looked at why the blood thinner clopidogrel is less effective in people over 70. Researchers measured levels of the drug's active metabolite and platelet function in 37 patients aged 50 to 100. The goal was to understand how age affects drug resistance, which could lead to safer use in older adults.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- clopidogrel
- What this could lead to
- If successful, this could help explain why clopidogrel is less effective in older adults and point toward better dosing or alternative treatments.
- What could go wrong
- This is a small, completed observational study with only 37 participants, so findings may not apply broadly. It does not test a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU de RENNES
Rennes, France
-
Hôpital Charles Foix
Paris, France
-
Hôpital Européen Georges Pompidou,
Paris, France
-
Hôpital Lariboisière
Paris, France
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