Heart ultrasound may reveal who gets the most from heart failure drug
NCT ID NCT07088471
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at 334 adults with heart failure and reduced pumping ability. Researchers used ultrasound to measure left atrial strain before and after starting sacubitril/valsartan, a drug known to improve survival. The goal was to see if these measurements could predict who responds best to the drug, potentially helping doctors tailor treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Sacubitril/valsartan (a combination drug that helps the heart work better)
What this could lead to
If successful, this could help doctors predict which heart failure patients will benefit most from sacubitril/valsartan, leading to more personalized treatment.
What could go wrong
This is a completed observational analysis, not a new treatment trial. The findings may not change practice directly and need further validation.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Connoly Hospital Blanchardstown
Dublin, Ireland