Study tests which aligner cleaner keeps your mouth healthiest

NCT ID NCT07307716

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study will test three ways to clean clear aligners: brushing with fluoride toothpaste, using chlorhexidine mouthwash, or using an oxygen-based cleanser. Twenty-one adults will try each method for one month to see how it affects bacteria and gum health. The goal is to find which cleaning method best prevents plaque buildup and gum problems during orthodontic treatment.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Chlorhexidine mouthwash (0.2%) and oxygen-based cleanser (BlueM)
What this could lead to
If successful, this could point toward the best cleaning method for clear aligners to reduce plaque and gum inflammation.
What could go wrong
This is a small, early-stage study with only 21 participants, so results may not apply to everyone. It looks at short-term changes, not long-term health outcomes.

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Conditions

The condition(s) this trial relates to.

Dental Plaque gingivitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Riyadh Elm University - Orthodontic Clinics

    Riyadh, Riyadh Region, Saudi Arabia

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