New clip device offers hope for leaky heart valve patients
NCT ID NCT03170349
First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 34 times
Summary
This study tested a new device called the Edwards PASCAL system to repair leaky mitral valves in the heart without open surgery. It involved 124 people with moderate-to-severe mitral regurgitation who were not good candidates for surgery. The device was placed using a thin tube through a blood vessel, and the study checked if it safely reduced the leak and improved symptoms. Results showed the device successfully reduced valve leakage in most patients, with few serious complications.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MITRAL VALVE REGURGITATION are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Carolinas Medical Center
Charlotte, North Carolina, 28203, United States
-
Cedars-Sinai Medical Center
Los Angeles, California, 90048, United States
-
Henry Ford Hospital
Detroit, Michigan, 48202, United States
-
Hygeia Hospital
Athens, 15123, Greece
-
Inselspital, University Hospital Bern
Bern, 3010, Switzerland
-
Metro North Hospital & Health Service, The Prince Charles Hospital
Brisbane, Chermside, QLD 4032, Australia
-
Morristown Medical Center
Morristown, New Jersey, 07960, United States
-
NorthShore University HealthSystem
Evanston, Illinois, 60201, United States
-
San Rafaelle Hospital
Milan, 20132, Italy
-
St Michael Hospital
Toronto, Ontario, M5B-1W8, Canada
-
St. Paul's Hospital, Providence Health Care Research Institute
Vancouver, British Columbia, V6E 1M7, Canada
-
Sunnybrook Hospital
Toronto, Ontario, M4N 3M5, Canada
-
Sydney Local Health District, Royal Prince Alfred Hospital
Camperdown, New South Wales, 2050, Australia
-
The Heart Hospital Baylor Plano
Plano, Texas, 75093, United States
-
Universitaetsklinikum Bonn, Medizinische Klinik II, Kardiologie
Bonn, 53127, Germany
-
University of Colorado Denver
Aurora, Colorado, 80045, United States
-
University of Virginia Health System
Charlottesville, Virginia, 22908, United States
Conditions
Explore the condition pages connected to this study.