Massive registry launched to monitor new heart valve procedure

NCT ID NCT02245763

Recruiting now Knowledge-focused Sponsor: American College of Cardiology Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This registry tracks the safety and real-world outcomes of a minimally invasive procedure to repair a leaky mitral valve (mitral regurgitation) using a device called a leaflet clip. It will enroll up to 4,000 patients across many hospitals. The goal is to monitor adverse events and understand how well the procedure works in everyday practice.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Leaflet Clip (device)
What this could lead to: If successful, this registry will provide real-world data on the safety and effectiveness of transcatheter mitral valve repair, helping guide future treatment decisions.
What could go wrong: This is an observational registry, not a controlled trial, so it cannot prove cause and effect. Results may be influenced by patient selection and reporting biases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

mitral valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MITRAL VALVE REGURGITATION

Contacts and locations

Locations

American College of Cardiology
RECRUITING

Washington D.C., District of Columbia, 20037, United States

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