New malaria drug shows promise against Drug-Resistant parasites

NCT ID NCT04675931

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 31 times

Summary

This study tested a new intravenous drug called cipargamin in 254 adults and children with severe malaria. The goal was to find a safe and effective dose, especially for cases resistant to current treatments. The drug works by quickly clearing malaria parasites from the blood, including drug-resistant strains.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Burkina Faso, 2208, Burkina Faso

  • Novartis Investigative Site

    Ouagadougou, Burkina Faso

  • Novartis Investigative Site

    Abidjan, 13BP972, Côte d’Ivoire

  • Novartis Investigative Site

    Agboville, BP 154, Côte d’Ivoire

  • Novartis Investigative Site

    Kinsasha, Democratic Republic of Congo, BP 7948, Democratic Republic of the Congo

  • Novartis Investigative Site

    Siaya, 2300, Kenya

  • Novartis Investigative Site

    Manhiça, Maputo Province, 1929, Mozambique

  • Novartis Investigative Site

    Kigali, BP 4560, Rwanda

  • Novartis Investigative Site

    Tororo, 10102, Uganda

Conditions

Explore the condition pages connected to this study.