Could cilostazol beat aspirin at preventing strokes?

NCT ID NCT07180472

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This study compares cilostazol, aspirin, and clopidogrel in 632 people who recently had a stroke due to cerebral small vessel disease. The goal is to see if cilostazol is better at preventing another stroke and slowing disease progression, with fewer bleeding risks. Participants will take one of the three drugs and be followed for outcomes like new strokes, cognitive decline, and disability.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Cilostazol
What this could lead to
If it works, this could provide a safer and more effective option to prevent recurrent strokes and slow cognitive decline in people with cerebral small vessel disease.
What could go wrong
This is a Phase 4 trial, but results may not apply to all patients. Cilostazol may not prove superior to existing drugs, and bleeding risks remain possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cerebral Small Vessel Diseases ischemic stroke prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.