Scientists track the earliest clues of a migraine before pain begins
NCT ID NCT07681466
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study investigates the sequence of early warning signs, called premonitory symptoms, that occur before a migraine headache starts. Researchers will follow 500 adults with migraine who will record their symptoms using an electronic diary for up to five attacks. The goal is to identify which symptoms appear first and how long before the headache they occur, which could help people better predict and manage their migraines.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help people with migraine recognize early signs and take preventive action sooner.
What could go wrong
This is an observational study, not a treatment trial. It may not lead to immediate clinical changes, and results depend on accurate self-reporting.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Atogepant vs Topiramate for Migraine Prevention NCT05748483
- Migraine Attack Prediction Study | NCT06459635
- Rimegepant for Migraine: Real-World Study NCT06467370
- Cocoa Flavanols for Migraine Pilot Study (NCT06808230)
- Fremanezumab for Migraine Prevention in Kids (NCT04458857)
- ASY202 Inhaled Migraine Treatment Trial (NCT07646613)
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sapienza University of Rome, Polo Pontino, centro cefalee, ICOT
RECRUITINGLatina, Italy, 04100, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact