Migraine device trial halted early – what we know
NCT ID NCT05843721
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study followed 98 people with chronic migraine who used a device that delivers gentle oscillations inside the nose. The goal was to see if regular use could cut down on severe headache days. The trial was terminated early, so the full results are not available, but the approach aimed to provide a non-drug option for migraine relief.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Intranasal kinetic oscillation stimulation device
What this could lead to
If effective, this device could offer a drug-free option to reduce migraine days for people with chronic migraine.
What could go wrong
The study was terminated early, so results are limited. It was also an uncontrolled trial, making it hard to know if benefits came from the device or chance.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Centro Regionale Diagnosi e Cura delle Cefalee IRCCS National Neurological Institute "C. Mondino" Foundation
Pavia, 27100, Italy
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Department of Neurology, Institute of Neurological Sciences, Queen Elizabeth University Hospital
Glasgow, G51 4TF, United Kingdom
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Hull Royal Infirmary, Hull University Teaching Hospital NHS Trust
Hull, HU3 2J, United Kingdom
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IRCCS Istituto Auxologico Italiano U.O. Neurologia - Centro Cefalee
Milan, 20149, Italy
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IRCCS San Raffaele Pisana Dipartimento di Scienze Neurologiche Motorie e Sensoriali Unità per la Cura e la Ricerca su Cefalee e Dolore
Roma, 00166, Italy
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Kopfschmerzzentrum Frankfurt
Frankfurt am Main, D-65929, Germany
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Policlinico Universitario Campus Bio-Medico di Roma UOC Neurologia
Roma, 00128, Italy
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Shaare Zedek Medical Center, Neurology Clinics,
Jerusalem, 9103102, Israel
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St. George's University Hospitals NHS Foundation Trust
London, SW17 0QT, United Kingdom
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Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden UniversitätsSchmerzCentrum
Dresden, D-01307, Germany
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Universitätsklinikum Essen (AöR) Klinik für Neurologie Kopfschmerz- und Schwindelambulanz
Essen, D-45147, Germany
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Universitätsklinikum Tübingen Klinik für Neurologie
Tübingen, D-72076, Germany