New cholera vaccine trial aims to protect south africans of all ages

NCT ID NCT07304284

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new oral cholera vaccine (Biovac OCV-S) to see if it works as well as a currently approved vaccine (Euvichol-Plus). About 2,824 healthy people aged 1 to 45, including some adults living with HIV, will receive two doses. Researchers will check immune responses and monitor for side effects over several months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease cholera prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Perinatal HIV Research Unit (PHRU)

    RECRUITING

    Johannesburg, Gauteng, 1862, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • SAMRC Chatworth CRS

    RECRUITING

    Durban, KwaZulu-Natal, 4092, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • SAMRC Isipingo CRS

    NOT_YET_RECRUITING

    Durban, KwaZulu-Natal, 4110, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Synergy Biomed Research Institute

    NOT_YET_RECRUITING

    Durban, Eastern Cape, 5201, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Wits Vaccines & Infectious Diseases Analytics (VIDA) Research Unit

    NOT_YET_RECRUITING

    Johannesburg, Gauteng, 1862, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••