Which antiseptic wins? new trial tests C-Section infection prevention

NCT ID NCT05920122

Completed Prevention Sponsor: Hyagriv Simhan Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two different skin cleansers used before cesarean sections to see which one better prevents wound infections. About 1,400 women having C-sections at one hospital were randomly assigned to get either a plain chlorhexidine solution or one mixed with alcohol. Researchers tracked infections within 30 days after surgery, along with other complications like endometritis and hospital readmissions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Chlorhexidine gluconate with isopropyl alcohol
What this could lead to: If one cleanser works better, hospitals may adopt it to reduce infections after C-sections, making surgery safer for mothers.
What could go wrong: This is a single-center study, so results may not apply everywhere. Both cleansers are already in use, so no major breakthrough is expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CESAREAN SECTION; INFECTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Infections puerperal infection Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CESAREAN SECTION; INFECTION SURGICAL SITE INFECTION

Contacts and locations

Locations

University of Pittsburgh

Pittsburgh, Pennsylvania, 15260, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.